verminderd resultaten van

93 billion

1 billion

31 million

406080

to ~263 options

options split into images, definition, symptoms, related diagnoses, diagnostic tests, therapies, and medications

wat is 'serum t4 free'? Definitie voor Serum T4 gratis Serum T4 gratis is ook bekend als: Vrij T4, Serum T4, Thyroxine T4, vrije thyroxine T4, totaal T4 Serum T4 free is een medische procedure gebruikt voor deze diagnoses als: De ziekte van Alzheimer, menopauze en Turner's Syndroom. related diagnosis for 'serum t4 gratis' 1 - 5 of 32 diagnose De ziekte van Alzheimer type of dementia in the elderly Serum T4 gratis en De ziekte van Alzheimer menopauze cessation of menstrual periods in women with advancing age Serum T4 gratis en menopauze Turner's Syndroom chromosomal condition causing underdevelopment of female sex characteristics Serum T4 gratis en Turner's Syndroom acute bijnierschorsinsufficiëntie decreased production of hormones from adrenal gland Serum T4 gratis en acute bijnierschorsinsufficiëntie constitutionele vertraging in de puberteit delayed puberty with no pathologic cause Serum T4 gratis en constitutionele vertraging in de puberteit hypofyse-adenoom type of brain tumor Serum T4 gratis en hypofyse-adenoom subacute thyroïditis inflammation of thyroid following upper respiratory infection Serum T4 gratis en subacute thyroïditis schildklier storm lifethreatening condition caused by uncontrolled production of excess thyroid hormone Serum T4 gratis en schildklier storm Hashimoto's thyroïditis autoimmune thyroid disorder Serum T4 gratis en Hashimoto's thyroïditis grondwettelijke korte gestalte variant of normal growth Serum T4 gratis en grondwettelijke korte gestalte struma enlarged thyroid gland Serum T4 gratis en struma hypercholesterolemie high cholesterol Serum T4 gratis en hypercholesterolemie hyperthyroïdie increased thyroid hormone in blood Serum T4 gratis en hyperthyroïdie hypertriglyceridemie increased blood fat Serum T4 gratis en hypertriglyceridemie hypothyreoïdie low thyroid hormone in blood Serum T4 gratis en hypothyreoïdie toxische adenoom van de schildklier excess thyroid hormone produced by nodule in thyroid gland Serum T4 gratis en toxische adenoom van de schildklier toxisch multinodulair struma increased thyroid hormone produced by nodules in thyroid gland Serum T4 gratis en toxisch multinodulair struma Cowden syndroom inherited multiple growths Serum T4 gratis en Cowden syndroom GEDICHTEN Syndroom rare multisystem disease causing nervous system, skin and endocrine problems Serum T4 gratis en GEDICHTEN Syndroom Sheehan's Syndroom post partum pituitary necrosis Serum T4 gratis en Sheehan's Syndroom voor meer kunt u inloggen, aanmelden is gratis (klik om in te loggen) related procedure for 'serum t4 gratis'/associated diagnoses 1 - 5 of 141 procedures Serum T3 Serum T4 gratis en Serum T3 Serum TSH Serum T4 gratis en Serum TSH Complete metabole paneel Serum T4 gratis en Complete metabole paneel serum elektrolyten Serum T4 gratis en serum elektrolyten Leverfunctietesten elevated liver enzymes Serum T4 gratis en Leverfunctietesten CT-scan Serum T4 gratis en CT-scan Complete bloedbeeld Serum T4 gratis en Complete bloedbeeld Follikel Stimulerend Hormoon FSH Serum T4 gratis en Follikel Stimulerend Hormoon FSH Leuteinizing hormoon LH Serum T4 gratis en Leuteinizing hormoon LH Serum cortisol Serum T4 gratis en Serum cortisol CT hersenen Serum T4 gratis en CT hersenen Serum creatinine Serum T4 gratis en Serum creatinine BUN Serum T4 gratis en BUN X-thorax Radiological technique to image the chest Serum T4 gratis en X-thorax ECG Electrocardiogram Serum T4 gratis en ECG Opname van radioactief jodium Serum T4 gratis en Opname van radioactief jodium Echocardiogram Serum T4 gratis en Echocardiogram Echografie nek Serum T4 gratis en Echografie nek Schildklier functie testen Serum T4 gratis en Schildklier functie testen T3 harsopname T3RU Serum T4 gratis en T3 harsopname T3RU voor meer kunt u inloggen, aanmelden is gratis (klik om in te loggen) related medication for 'serum t4 gratis'/associated diagnoses 1 - 5 of 141 drugs propranolol Serum T4 gratis en propranolol propylthiouracil Serum T4 gratis en propylthiouracil levothyroxine Serum T4 gratis en levothyroxine propranolol(inderal) Serum T4 gratis en propranolol(inderal) dexamethasone Serum T4 gratis en dexamethasone methimazole Serum T4 gratis en methimazole esterified estrogens(menest , estratab) Serum T4 gratis en esterified estrogens(menest , estratab) estradiol(estrace) Serum T4 gratis en estradiol(estrace) progesterone(prometrium) Serum T4 gratis en progesterone(prometrium) activella Serum T4 gratis en activella alendronate Serum T4 gratis en alendronate antidepressants Serum T4 gratis en antidepressants aygestin Serum T4 gratis en aygestin calcium 1,200 mg Serum T4 gratis en calcium 1,200 mg cholineterase inhibitors Serum T4 gratis en cholineterase inhibitors clonidine Serum T4 gratis en clonidine clonidine(catapres) Serum T4 gratis en clonidine(catapres) combipatch Serum T4 gratis en combipatch conjugated estrogens topical(premarin vaginal ) Serum T4 gratis en conjugated estrogens topical(premarin vaginal ) conjugated estrogens(premarin) Serum T4 gratis en conjugated estrogens(premarin) voor meer kunt u inloggen, aanmelden is gratis (klik om in te loggen) De volgende soorten van artsen die relevant zijn voor 'Serum T4 gratis'. samenhangende vormen van artsen 'family practitioner, internist' show local physicians postcode Find Local sterren zijn relevantie voor het onderwerp geen rating meer De resultaten zijn computer gegenereerde suggesties om u te helpen een arts. MEDgle niet aanbevelen een bepaald type van arts of vordering volledig te zijn of juist in de aanbieders en specialiteiten voorgesteld. zoekresultaten voor 'serum t4 gratis'? Resultaten 1 - 50 - Serum T4 free Normal serum free thyroid hormone concentrations in patients treated ... [Vertaal deze pagina] MAIN OUTCOME MEASURE: Serum concentrations of free T4 and free T3 in patients ... Free T4 concentration measured by a commercial kit (1:5 serum dilution) was ... http://www.ncbi.nlm.nih.gov/pubmed/8622224   www.ncbi.nlm.nih.gov - summary Levothyroxine therapy and serum free thyroxine and free ... [Vertaal deze pagina] In groups A and B, mean serum free T4 and free T3 were very similar. ... is sufficient to maintain a normal serum TSH, is accompanied by a serum free T4 ... http://www.ncbi.nlm.nih.gov/pubmed/11929079?dopt=Abstract   www.ncbi.nlm.nih.gov - summary Serum concentrations of total and free thyroid hormones in moderately ... [Vertaal deze pagina] ... of serum total (T4) and free (FT4) thyroxine, total (T3) and free (FT3) 3, ... The largest decreases in serum T4, T3 and FT3 observed during the cure occurred ... http://www.ncbi.nlm.nih.gov/pubmed/3396520   www.ncbi.nlm.nih.gov - summary Thyroid Blood Tests - Diagnosing Thyroid Disease With Blood Tests [Vertaal deze pagina] Free or unbound T4 levels represent the level of hormone available for uptake and use by cells. ... Total T4/Total Thyroxine/Serum Thyroxine ... http://thyroid.about.com/od/gettestedanddiagnosed/a/bloodtests.htm   thyroid.about.com - summary ATSDR -Evaluation of diabetes mellitus, serum glucose, and thyroid ... [Vertaal deze pagina] ... serum TCDD concentrations had the highest adjusted mean free T4 index, which was ... TSH, T4, and free T4 index (FTI) by TCDD category in serum samples ... http://www.atsdr.cdc.gov/NER/JOURNAL/jad11190302.html   www.atsdr.cdc.gov - summary Di(2-ethylhexyl) Phthalate Metabolites May Alter Thyroid Hormone Levels ... [Vertaal deze pagina] ... between MEHP urinary concentrations and free T4 and T3 serum levels, although ... Free T4, total T3, and TSH concentrations were determined in serum by ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...   www.pubmedcentral.nih.gov - summary Serum total thyroxine, total triiodothyronine, free thyroxine, and ... [Vertaal deze pagina] PROCEDURE: Serum total T4, total T3, free T4, and TSH concentrations were ... low serum concentrations of total T4, total T3, or free T4 more commonly than ... http://www.ncbi.nlm.nih.gov/pubmed/11561650?ordinalpos=1&ito...   www.ncbi.nlm.nih.gov - summary Thyroxine - Wikipedia, the free encyclopedia [Vertaal deze pagina] ... T3 and T4 section of ... and, to a lesser extent, to transthyretin and serum albumin. ... under the terms of the GNU Free Documentation License. ... http://en.wikipedia.org/wiki/Thyroxine   en.wikipedia.org - summary Postnatal thyroid hormones for preterm infants with transient ... [Vertaal deze pagina] In preterm infants, values for serum T4 and free T4 (FT4) in the first days ... the transient decrease in serum concentration of free T4 that occurs in some ... http://www.nichd.nih.gov/cochrane/Osborn11/osborn11.htm   www.nichd.nih.gov - summary Thyroid Hormone Tests [Vertaal deze pagina] Thyroid hormone tests are blood tests that check how well the thyroid gland is working. ... A total T4 blood test measures both bound and free thyroxine. ... http://www.webmd.com/a-to-z-guides/thyroid-hormone-tests   www.webmd.com - summary Assessment of Thyroid Function: Towards an Integrated Laboratory ... [Vertaal deze pagina] The serum TSH response to changes in serum free T4 is logarithmic; a two-fold ... there is a diagnostic change in serum free T4. ... Estimation of Serum Free T4 ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1853349   www.pubmedcentral.nih.gov - summary Thyroid Hormone Binding by Human Serum Prealbumin (TBPA ... [Vertaal deze pagina] ... PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins. ... of thyroxine(T4)-binding proteins of human serum in polyacrylamide gel ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=302156   www.pubmedcentral.nih.gov - summary Significant inverse relationship between serum free T4 concentration ... [Vertaal deze pagina] ... inverse relationship between serum free T4 concentration and body mass ... were used to examine the relationships between serum free T4, serum TSH, BMI and ... http://www.ncbi.nlm.nih.gov/pubmed/18346211   www.ncbi.nlm.nih.gov - summary Thyroxine transport and distribution in Nagase analbuminemic rats. [Vertaal deze pagina] ... rats, all of whom had similar serum T4 concentrations and percent free T4 values. ... of free fatty acids on the concentration of free thyroxine in human ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=303654   www.pubmedcentral.nih.gov - summary Radioimmunoassay of free thyroxine (T4) using 125I-labeled T4-IgG ... [Vertaal deze pagina] ... antibody radioimmunoassay for the determination of free thyroxine (FT4) in serum ... with those obtained by a free T4-equilibrium dialysis kit (Nichols) ... http://www.ncbi.nlm.nih.gov/pubmed/8714438   www.ncbi.nlm.nih.gov - summary The T4-free thyroxine index as a test of thyroid function of first choice [Vertaal deze pagina] The T4-free thyroxine index was used as the thyroid function test of first ... of serum-total-thyroxine estimation, resin uptake, and free-thyroxine index. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=477274   www.pubmedcentral.nih.gov - summary Thyroid Function Tests -- Clinical Methods -- NCBI Bookshelf [Vertaal deze pagina] ... settings measurement of the serum concentration of free T4 by dialysis may be ... T4: total serum thyroxine. T3RU: T3 resin uptake. FT4I: free thyroxine index. ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cm&part=A4228   www.ncbi.nlm.nih.gov - summary Effects of prednisone on thyroxine and 3,5,3'-triiodothyronine ... [Vertaal deze pagina] ... pools (to 7%) to serum, and increased serum free T4 clearance rates (to 144%) as ... T3 production from T4, resulting in reduced serum total and free T3 levels. ... http://www.ncbi.nlm.nih.gov/pubmed/1537315   www.ncbi.nlm.nih.gov - summary Urinary Perchlorate and Thyroid Hormone Levels in Adolescent and Adult ... [Vertaal deze pagina] Serum samples collected in 2002 were assayed for TSH and T4 by Collaborative ... Finally, a measurement of free T4 would be an improvement to the study. Top ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1764147   www.pubmedcentral.nih.gov - summary MedlinePlus Medical Encyclopedia: Hypothyroidism - primary [Vertaal deze pagina] Free T4 or free thyroxine index (low) Free T4 test (low) Serum thyroid stimulating hormone (TSH) (high) Other problems found on lab tests may include: ... http://www.nlm.nih.gov/medlineplus/ency/article/000367.htm   www.nlm.nih.gov - summary The effect of D- and L-thyroxine on sex hormone-binding globulin in rabbits. [Vertaal deze pagina] Serum concentrations of L-T4 cholesterol, E2, progesterone, free and total ... Values for serum T4, T, percent free T, free T, E2, progesterone and cholesterol ... http://www.ncbi.nlm.nih.gov/pubmed/6541121   www.ncbi.nlm.nih.gov - summary Toll-like receptor-MyD88 and Fc receptor pathways of mast cells mediate ... [Vertaal deze pagina] Serum T4, T3, and TSH decrease, reaching a nadir after 6 h, and then return to ... These free T4 results, obtained by using a competitive RIA kit, were confirmed ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1851609   www.pubmedcentral.nih.gov - summary Development of a highly sensitive and selective microplate ... [Vertaal deze pagina] ... between the free and protein-bound fractions of T4, bringing bad ... Determination of free thyroxine in serum by low-temperature equilibrium dialysis. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1865090   www.pubmedcentral.nih.gov - summary Changes in serum thyroid hormone, thyrotropin and thyroglobulin ... [Vertaal deze pagina] The mean serum T4, free T4, free T3, and rT3 concentrations increased ... findings demonstrate that serum Tg levels decrease when T4 therapy is effective. ... http://www.ncbi.nlm.nih.gov/pubmed/2753971?ordinalpos=47&ito...   www.ncbi.nlm.nih.gov - summary The MCT8 thyroid hormone transporter and Allan--Herndon--Dudley syndrome [Vertaal deze pagina] ... and total and free T4 levels at the lower end of normal; serum TSH levels varied ... high levels of serum free T3, rather low levels of serum T4, and a TSH ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2094733   www.pubmedcentral.nih.gov - summary 6804476 1982 07 19 1982 07 19 2005 11 17 0021-972X 54 6 1982 Jun J ... [Vertaal deze pagina] Serum resin T3 uptake, T4, free T4 index(FT4I), T3, free T3 index, and rT3 ... Basal and peak TSH after TRH were inversely correlated with serum T4 and FT4I levels. ... http://www.ncbi.nlm.nih.gov/pubmed/6804476   www.ncbi.nlm.nih.gov - summary Reduced peripheral conversion of thyroxine to triiodothyronine in ... [Vertaal deze pagina] ... (TSH) and total and free T4 and T3 in randomand serial serum samples. ... The reduction of the serum total and free T3 values were closely correlated with ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=301912   www.pubmedcentral.nih.gov - summary THE MERCK MANUAL OF GERIATRICS, Ch. 65, Thyroid Disorders [Vertaal deze pagina] Serum T4 and T3 levels are no higher than in patients with usual degrees of ... With more serious disease, the serum T4 and free T4 index may also decline into ... http://www.merck.com/mkgr/mmg/sec8/ch65/ch65c.jsp   www.merck.com - summary Serum levels of free and bound testosterone in hyperthyroidism. [Vertaal deze pagina] MEASUREMENTS: The serum concentrations of free T3, free T4, TSH, sex hormone ... For women, the mean free testosterone concentration was significantly lower ... http://www.ncbi.nlm.nih.gov/pubmed/1568351?ordinalpos=4&itoo...   www.ncbi.nlm.nih.gov - summary Effects of EDTA and Sodium Citrate on hormone measurements by ... [Vertaal deze pagina] ... significant differences were seen between samples for LH, FSH, PRL and free T4. ... always be carried out in serum, free of metal-complexing anticoagulant, thus ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=115861   www.pubmedcentral.nih.gov - summary The acute effect of calcium carbonate on the intestinal absorption of ... [Vertaal deze pagina] Serum total T4, total triiodothyronine (T3), free T4, and thyrotropin (TSH) ... serum total T4 (p = 0.02) and free T4 levels (p = 0.03), as well as a ... http://www.ncbi.nlm.nih.gov/pubmed/11716045   www.ncbi.nlm.nih.gov - summary 2579968 1985 05 10 1985 05 10 2006 11 15 0021-972X 60 5 1985 May J ... [Vertaal deze pagina] ... serum showed that about 10 micrograms/ml furosemide increased the free T4 and free T3 fractions. ... furosemide is unlikely to decrease serum T4 or T3. ... http://www.ncbi.nlm.nih.gov/pubmed/2579968?ordinalpos=57&ito...   www.ncbi.nlm.nih.gov - summary Benchmark Calculations for Perchlorate from Three Human Cohorts [Vertaal deze pagina] ... from thyroid-stimulating hormone (TSH) and free thyroxine (T4) serum indicators ... hormones, and they can be either bound to serum proteins or free. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1280340   www.pubmedcentral.nih.gov - summary Eastern Mediterranean Health Journal [Vertaal deze pagina] However, free T4 levels were not significantly different between groups (P = 0.9) ... deficiency disorder (free T3, free T4 serum TSH, serum thyroglobulin and ... http://www.emro.who.int/publications/emhj/1006/Urinary.htm   www.emro.who.int - summary A Lab's Normal TSH, T4, T3 Levels May be Abnormal for You-- March 2002 [Vertaal deze pagina] ... levels -- T4, T3, free T4 index, and TSH -- of 16 healthy men with over ... Reference: "Narrow Individual Variations in Serum T4 and T3 in Normal Subjects: ... http://thyroid.about.com/cs/testsforthyroid/l/blnormalforyou.htm   thyroid.about.com - summary Introduction: Thyroid Disorders: Merck Manual Professional [Vertaal deze pagina] Total serum T4 is a measure of bound and free hormone. ... Free T4 in the serum can be measured directly, avoiding the pitfalls of ... http://www.merck.com/mmpe/print/sec12/ch152/ch152a.html   www.merck.com - summary Prophylactic postnatal thyroid hormones for prevention of morbidity and ... [Vertaal deze pagina] In preterm infants, levels of serum T4 and free T4 in the first days after birth ... the transient decrease in serum concentration of free T4 that occurs in some ... http://www.nichd.nih.gov/COCHRANE/Osborn14/osborn14.htm   www.nichd.nih.gov - summary Structural basis of albumin?thyroxine interactions and familial ... [Vertaal deze pagina] ... have normal serum levels of free T4, but their total serum T4 is significantly ... and reconcentrated at least twice to ensure a free T4 concentration of 0.1 mM. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=164465   www.pubmedcentral.nih.gov - summary Effect of epinephrine on the peripheral metabolism of thyroxine [Vertaal deze pagina] Stable serum T4 iodine decreased during the experiment. ... method for measuring the free thyroid hormone in human serum and an analysis of ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=322326   www.pubmedcentral.nih.gov - summary The thyroid gland -- Endocrinology -- NCBI Bookshelf [Vertaal deze pagina] In this patient, the serum total T4 was raised whilst free T3 and TSH were ... Her free T4 was 55 pmol/l and the serum TSH was unmeasurable (<0.05 mU/l) ... http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=endocrin.section.332   www.ncbi.nlm.nih.gov - summary Diagnosis and treatment of the solitary thyroid nodule. Results of a ... [Vertaal deze pagina] ... basal serum TSH was the routine choice of 99% and serum T4 and/or free T4 were ... determinations of serum TSH combined with serum T4 and/or free T4 followed by ... http://www.ncbi.nlm.nih.gov/pubmed/10435062   www.ncbi.nlm.nih.gov - summary Hyperthyroidism: Thyroid Disorders: Merck Manual Professional [Vertaal deze pagina] ... decrease in serum TSH and mild increase in serum free T4 sometimes observed ... circulating free T4 and T3 concentrations and normal or elevated serum TSH. ... http://www.merck.com/mmpe/print/sec12/ch152/ch152e.html   www.merck.com - summary Cortisol and free thyroxine determination by time-resolved fluorometry ... [Vertaal deze pagina] ... serum thyroid-stimulating hormone (TSH) and total thyroxine (tT4) or free T4 ... Evaluation of serum free thyroxine and thyrotropin concentrations in the ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1142152   www.pubmedcentral.nih.gov - summary Thyroid functions of mouse cathepsins B, K, and L [Vertaal deze pagina] Blood sample collection and quantitation of serum T4 levels. ... determination of serum levels of free T4 (FT4), serum samples were analyzed in ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=156100   www.pubmedcentral.nih.gov - summary The thyroid gland -- Endocrinology -- NCBI Bookshelf [Vertaal deze pagina] Free T4 in patient's serum is captured on antibodies, and hormones bound to ... The direct measurement of free T4 and T3 requires physical removal of bound ... http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=endocrin&...   www.ncbi.nlm.nih.gov - summary Effects of grapefruit juice on the absorption of levothyroxine [Vertaal deze pagina] The incremental areas under the serum T4 concentration-time curve (dAUC) during ... Only subjects with serum concentrations of TSH and free thyroxine within the ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1884777   www.pubmedcentral.nih.gov - summary Decreased peripheral 3,5,3'-triiodothyronine (T3) production from ... [Vertaal deze pagina] ... been performed in a T4-substituted female who showed an increased serum T4/T3 ... elevated serum free T4 level, serum TSH was elevated, pointing to T4 transport ... http://www.ncbi.nlm.nih.gov/pubmed/8077346?dopt=Abstract   www.ncbi.nlm.nih.gov - summary A fatal case of recurrent amiodarone-induced thyrotoxicosis after ... [Vertaal deze pagina] ... later (Figure 1), while serum free T4 and free T3 decreased promptly (FT4: 5.5 ... sudden decrease in serum TSH, along with high free T4 and T3concentrations can ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2194711   www.pubmedcentral.nih.gov - summary THE MERCK MANUAL OF GERIATRICS, Ch. 65, Thyroid Disorders [Vertaal deze pagina] Serum free T4 should be measured to differentiate overt hypothyroidism ... The serum free T4 level is, by definition, within the normal range but tends to ... http://www.merck.com/mkgr/mmg/sec8/ch65/ch65b.jsp   www.merck.com - summary Relating circulating thyroid hormone concentrations to serum ... [Vertaal deze pagina] ... of total thyroxine (T4), elevated concentrations of absolute free T4, and ... collected for measurement of serum IL-6, IL-10, TSH, T3, and total T4 levels. ... http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2254394   www.pubmedcentral.nih.gov - summary toon meer 1  2

Chat with eNurse Kim about 'Serum T4 gratis' or something else! snelle feiten related diagnosis category endocrine vrouwelijk voortplantingssysteem-gynaecologische geriatric problemen mannelijke voortplantingssysteem metabole