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apc resistentie - conditie die verhoogde bloedstolling
Definitie voor APC resistentie
Activated protein C resistance is a hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC).
meer
Activated protein C resistance is a hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). This results in an increased risk of venous thrombosis.
Activated protein C (with protein S as a cofactor) degrades Factor Va and Factor VIIIa. Activated protein C resistance is the inability of protein C to cleave Factor Va and/or Factor VIIIa, which allows for longer duration of thrombin generation and may lead to a hypercoagulable state. This may be hereditary or acquired. The best known and most common hereditary form is Factor V Leiden. Acquired forms occur in the presence of elevated Factor VIII concentrations.
less
enkele veel voorkomende symptomen
pijn in de benen
gezwollen voet
gezwollen been
zweren op de benen en voeten
sommige gerelateerde diagnoses
1 - 7 of
31
diagnoses
Factor V Leiden trombofilie
diepe veneuze trombose
trauma
diabetische neuropathie
spataderen
stammen en verstuikingen
baarmoederhalskanker
meer
heb ik 'APC resistentie'?
Bovendien moeten de volgende diagnostische tests kunnen worden moeten helpen controleren of de diagnose:
diagnostische test zoekresultaten voor 'apc resistentie'
1 - 5 of
34
diagnostische tests
Geactiveerd Proteïne C resistentie te testen
clotting assay to define a cause of increased clotting
APC resistentie en Geactiveerd Proteïne C resistentie te testen
Antifosfolipiden antilichamen
anribodies seen in inappropriate clot formation
APC resistentie en Antifosfolipiden antilichamen
Antitrombine III
clot thinning factor in body
APC resistentie en Antitrombine III
Kleur flow duplex scannen
APC resistentie en Kleur flow duplex scannen
D-dimeren
APC resistentie en D-dimeren
Doppler echografie
APC resistentie en Doppler echografie
Duplex echografie
APC resistentie en Duplex echografie
Factor V Leiden mutatie
APC resistentie en Factor V Leiden mutatie
Lupus anticoagulans
APC resistentie en Lupus anticoagulans
Methylenetetrahydrofolate reductase mutatie
APC resistentie en Methylenetetrahydrofolate reductase mutatie
Proteïne C antigeen en activiteit
APC resistentie en Proteïne C antigeen en activiteit
Proteïne S
APC resistentie en Proteïne S
Geactiveerde partiële tromboplastine tijd
APC resistentie en Geactiveerde partiële tromboplastine tijd
Arteriële bloedgas
APC resistentie en Arteriële bloedgas
Bloed, bloedplaatjes
Platelet Count
APC resistentie en Bloed, bloedplaatjes
Hartbewaking
APC resistentie en Hartbewaking
Complete bloedbeeld
APC resistentie en Complete bloedbeeld
Compressie echografie
APC resistentie en Compressie echografie
Protrombinetijd PT
APC resistentie en Protrombinetijd PT
Pulsoximetrie
Oximetry
APC resistentie en Pulsoximetrie
Echografie van het been
APC resistentie en Echografie van het been
veneuze Doppler studies
APC resistentie en veneuze Doppler studies
CT-scan
APC resistentie en CT-scan
CT venografie
APC resistentie en CT venografie
Protrombine 20210A mutatie
APC resistentie en Protrombine 20210A mutatie
Serumhomocysteïne
APC resistentie en Serumhomocysteïne
urine-output
APC resistentie en urine-output
Contrast venografie
APC resistentie en Contrast venografie
MRI Magnetic Resonance Imaging
APC resistentie en MRI Magnetic Resonance Imaging
radio-isotopen venografie
APC resistentie en radio-isotopen venografie
Heparine-geïnduceerde antilichaam testen
APC resistentie en Heparine-geïnduceerde antilichaam testen
activiteit en antigeniciteit van plasminogeen
APC resistentie en activiteit en antigeniciteit van plasminogeen
bloedplaatjes morfologie
APC resistentie en bloedplaatjes morfologie
Impedantie plethysmografie
APC resistentie en Impedantie plethysmografie
voor meer kunt u inloggen, aanmelden is gratis (klik om in te loggen)
therapeutische procedures voor 'APC resistentie'?
Beheren of de behandeling van een ziekte moet altijd worden bepaald door een patiënten zorgverstrekker. Hieronder is een lijst van de bijbehorende procedures of therapeutische medicijnen voor APC resistance:
therapeutische procedure zoekresultaten voor 'apc resistentie'
1 - 4 of
4
therapeutische procedures
rankings zijn computer gegenereerd. raadpleeg uw zorgverlener.
Compressie kousen
APC resistentie en Compressie kousen
stolsel verwijderen en de gedeeltelijke onderbreking van de vena cava inferior
APC resistentie en stolsel verwijderen en de gedeeltelijke onderbreking van de vena cava inferior
Inferior Vena Caval Filter
APC resistentie en Inferior Vena Caval Filter
Zuurstof
APC resistentie en Zuurstof
medicatie zoekresultaten voor 'apc resistentie'
1 - 5 of
20
medicatie
rankings zijn computer gegenereerd. raadpleeg uw zorgverlener.
Heparin
APC resistentie en Heparin
tPA
APC resistentie en tPA
Warfarin
APC resistentie en Warfarin
warfarin
APC resistentie en warfarin
Urokinase
APC resistentie en Urokinase
rPA
APC resistentie en rPA
Streptokinase
APC resistentie en Streptokinase
Enoxaparin
APC resistentie en Enoxaparin
Dalteparin
APC resistentie en Dalteparin
Alteplase
APC resistentie en Alteplase
Tinzaparin
APC resistentie en Tinzaparin
Fondaparinux sodium
APC resistentie en Fondaparinux sodium
Tenecteplase
APC resistentie en Tenecteplase
Dalteparin
(a.k.a Dalteparin, Fragmin)
APC resistentie en Dalteparin
Nadroparin
(a.k.a Nadroparin, Fraxiparin)
APC resistentie en Nadroparin
Reviparin
(a.k.a Reviparin, Clivarin)
APC resistentie en Reviparin
Enoxaparin
(a.k.a Enoxaparin, Lovenox andClexane)
APC resistentie en Enoxaparin
Ardeparin
(a.k.a Ardeparin, Normiflo)
APC resistentie en Ardeparin
Certoparin
(a.k.a Certoparin, Sandoparin)
APC resistentie en Certoparin
Tinzaparin
(a.k.a Tinzaparin, Innohep and Logiparin)
APC resistentie en Tinzaparin
voor meer kunt u inloggen, aanmelden is gratis (klik om in te loggen)
zoekresultaten voor apc resistentie
Web (Alle)
|
Behandeling
|
Drugs
|
Tests
|
Onderzoek
|
Dieet
Resultaten
1 - 50
- APC-resistentie
APC resistance in an elite female athlete.
[
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This is the first documented case of APC resistance in an elite female athlete. ... or a thromboembolic event must be initiated in case of known APC resistance. ...
http://www.ncbi.nlm.nih.gov/pubmed/9502342?ordinalpos=3&itoo...
www.ncbi.nlm.nih.gov
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summary
Diagnosis of APC resistance in patients on standard or low molecular ...
[
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1: Thromb Haemost. 1996 Feb;75(2):372-3. Diagnosis of APC resistance in patients on standard or low molecular weight heparin. ...
http://www.ncbi.nlm.nih.gov/pubmed/8815593
www.ncbi.nlm.nih.gov
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summary
Factor V Leiden thrombophilia - Genetics Home Reference
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... with the factor V Leiden mutation, APC is unable to inactivate factor V normally. ... APC resistance, Leiden type. Hereditary resistance to activated protein C ...
http://ghr.nlm.nih.gov/condition=factorvleidenthrombophilia
ghr.nlm.nih.gov
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summary
Genomics|Genetic Testing|FBR|VTE|Disorder Setting
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The mission of the National Office of Public Health Genomics is to integrate advances in human genetics into public ... causes of APC resistance besides the ...
http://www.cdc.gov/genomics/gtesting/ACCE/FBR/VTE/VTEDisSet.htm
www.cdc.gov
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summary
Factor V Leiden Thrombophilia
[
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The "original" APC resistance assay involves performing an aPTT on the ... Resistance to APC resulting from factor V Leiden may be acquired or corrected by ...
http://www.ncbi.nlm.nih.gov/bookshelf/picrender.fcgi?book=ge...
www.ncbi.nlm.nih.gov
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summary
F5 - coagulation factor V (proaccelerin, labile factor) - Genetics Home ...
[
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... factor V from working with APC to inactivate factor VIIIa. ... This condition is known as pseudo-homozygous APC resistance. Where is the F5 gene located? ...
http://ghr.nlm.nih.gov/gene=f5
ghr.nlm.nih.gov
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summary
Genomics|Population Research|Health Studies|Genetic Traits and Venous ...
[
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The mission of the National Office of Public Health Genomics is to integrate advances in human genetics into ... APC response, termed APC resistance (APC ...
http://www.cdc.gov/genomics/population/publications/venous.htm
www.cdc.gov
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summary
Activated protein C resistance - Wikipedia, the free encyclopedia
[
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Activated protein C resistance is a hemostatic disorder characterized by a poor ... T = Thrombin, PC= Protein C, Activated Protein C= APC, PS= Protein S ...
http://en.wikipedia.org/wiki/Activated_protein_C_resistance
en.wikipedia.org
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summary
Thrombin-activatable fibrinolysis inhibitor antigen and TAFI activity ...
[
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TAFI activity was significantly reduced in APC resistance patients compared to control (P=.018) ... increased in patients with APC resistance due to FV Leiden ...
http://www.ncbi.nlm.nih.gov/pubmed/12165290
www.ncbi.nlm.nih.gov
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summary
F5 - References - Genetics Home Reference
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... V allele modulates the APC resistance phenotype in heterozygous carriers of ... Activated protein C resistance and factor V Leiden: a review. Arch Pathol Lab Med. ...
http://ghr.nlm.nih.gov/gene=f5/show/References
ghr.nlm.nih.gov
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summary
The discovery of activated protein C resistance.
[
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APC resistance was discovered in my laboratory in the late 1980s and we ... Analyses for APC resistance and FV Leiden have made their way into clinical ...
http://www.ncbi.nlm.nih.gov/pubmed/12871530
www.ncbi.nlm.nih.gov
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summary
Genomics|Population Research|Health Studies|Protein C and Venous Thrombosis
[
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The mission of the National Office of Public Health Genomics is to integrate advances in human genetics into ... APC-resistance as an additional risk factor ...
http://www.cdc.gov/genomics/population/publications/protein_c.htm
www.cdc.gov
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summary
Congenital and acquired activated protein C resistance.
[
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Resistance to the anticoagulant action of activated protein C, APC resistance, ... In most cases, APC resistance is associated with a single missense mutation in ...
http://www.ncbi.nlm.nih.gov/pubmed/15199491
www.ncbi.nlm.nih.gov
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summary
Thrombotic Disorders: Hematology and Oncology: Merck Manual Professional
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Factor V Resistance to Activated Protein C. Protein C Deficiency. Protein S Deficiency ... APC degrades factors Va and VIIIa, thus inhibiting coagulation. ...
http://www.merck.com/mmpe/sec11/ch135/ch135a.html
www.merck.com
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summary
The prevalence of poor anticoagulant response to activated protein C ...
[
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The prevalence of APC resistance was found to be significantly higher among ... functional protein S assay and APC resistance (represented by the ratio (Rs ...
http://www.ncbi.nlm.nih.gov/pubmed/8180338
www.ncbi.nlm.nih.gov
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summary
ClinicalHistoryForm-forPlatelets
[
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initiated "Diagnostic Interpretive Testing", where the laboratory results in the ... PT, PTT, Fibrinogen, Cardiolipin antibody panel, APC-resistance, ...
http://referencelab.clevelandclinic.org/images/ClinicalHisto...
referencelab.clevelandclinic.org
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summary
Resistance to activated protein C in women using oral contraceptives.
[
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The majority of patients with APC resistance carry a mutation on the factor V ... Thus, APC resistance is significantly lower in OC users than in nonusers but ...
http://www.ncbi.nlm.nih.gov/pubmed/9834008
www.ncbi.nlm.nih.gov
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summary
Blood/lymphatic system - Genetics Home Reference
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APC resistance, Leiden type see factor V Leiden thrombophilia ... Hereditary resistance to activated protein C see factor V Leiden thrombophilia ...
http://ghr.nlm.nih.gov/conditionCategory=bloodlymphaticsystem
ghr.nlm.nih.gov
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summary
Thromboembolism and resistance to activated protein C in patients with ...
[
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Resistance of factor V to degradation by activated protein C (APC) is a major ... Five (31.3%) of them had APC resistance, which was more common than in patients ...
http://www.ncbi.nlm.nih.gov/pubmed/10086652
www.ncbi.nlm.nih.gov
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summary
Thrombotic Disorders: Hematology and Oncology: Merck Manual Professional
[
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Factor V Resistance to Activated Protein C. APC degrades factors Va and VIIIa, thus inhibiting coagulation. ... a cofactor for APC-mediated cleavage of factors ...
http://www.merck.com/mmpe/print/sec11/ch135/ch135a.html
www.merck.com
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summary
Low-dose oral contraceptives and acquired resistance to activated ...
[
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... increased resistance to the anticoagulant action of activated protein C (APC) ... Whether acquired APC resistance induced by oral contraceptives explains the ...
http://www.ncbi.nlm.nih.gov/pubmed/10636369
www.ncbi.nlm.nih.gov
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summary
Activated protein C resistance in the absence of factor V Leiden ...
[
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The risk of DVT was highest (50%) in patients with APC resistance on thalidomide. ... conclusion, in this series, acquired APC resistance was present in almost one ...
http://www.ncbi.nlm.nih.gov/pubmed/11943931
www.ncbi.nlm.nih.gov
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summary
15947551 2005 06 10 2006 01 09 0954-691X 17 7 2005 Jul Prevalence of ...
[
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... C (APC) resistance and prothrombin gene mutations as well as vitamin ... APC resistance was measured using an unmodified activated partial thromboplastin ...
http://www.ncbi.nlm.nih.gov/pubmed/15947551
www.ncbi.nlm.nih.gov
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summary
PMID 16645152
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... on activated protein C (APC) resistance and other hemostatic parameters ... (nAPCsr) were determined with a thrombin generation-based APC resistance test. ...
http://www.ncbi.nlm.nih.gov/pubmed/16645152
www.ncbi.nlm.nih.gov
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summary
Long-chain n-3 fatty acid supplementation in men increases resistance ...
[
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... that resistance to the anticoagulant, activated protein C (APC), be considered ... The decrease in APC ratio equates to an increase in APC resistance. ...
http://www.ncbi.nlm.nih.gov/pubmed/17379015
www.ncbi.nlm.nih.gov
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summary
PMID 8164741
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... 5% of healthy individuals show APC resistance, which is associated with a ... that the phenotype of APC resistance is associated with heterozygosity or ...
http://www.ncbi.nlm.nih.gov/pubmed/8164741
www.ncbi.nlm.nih.gov
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summary
Different effects of oral and transdermal hormone replacement therapies ...
[
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... APC resistance, t-PA, PAI and C-reactive protein--a cross-sectional population survey. ... of Factor IX, activated protein C (APC) resistance, and CRP; and ...
http://www.ncbi.nlm.nih.gov/pubmed/11522002
www.ncbi.nlm.nih.gov
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summary
17179822 2006 12 20 2007 03 05 0957-5235 18 1 2007 Jan Blood Coagul ...
[
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Resistance against activated protein C (APC), assessed by a thrombin generation ... This acquired form of APC resistance was due to proinflammatory changes ...
http://www.ncbi.nlm.nih.gov/pubmed/17179822
www.ncbi.nlm.nih.gov
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summary
CancerLIT: 704301
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... the lack of cross resistance to immunologic-based therapeutics. ... assay for activated protein C (APC) resistance or polymerase chain reaction (PCR) ...
http://cancerweb.ncl.ac.uk/cancernet/cancerlit/704301.html
cancerweb.ncl.ac.uk
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summary
Factor V Cambridge: a new mutation (Arg306-->Thr) associated with ...
[
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... venous thrombosis and confirmed APC resistance in the absence of the ... Other potential causes of APC resistance, such as a mutation at the Arg679 site ...
http://www.ncbi.nlm.nih.gov/pubmed/9454742
www.ncbi.nlm.nih.gov
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summary
9645913 1998 09 01 1998 09 01 2007 11 15 0049-3848 89 5 1998 Mar 1 ...
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... based method for determination of APC resistance in plasma from patients on ... APTT-based kit method (Coatest APC Resistance), modified by predilution 1+4 of ...
http://www.ncbi.nlm.nih.gov/pubmed/9645913
www.ncbi.nlm.nih.gov
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summary
Genomics|HuGENet|Literature|2008 May 8
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The mission of the National Office of Public Health Genomics is to integrate ... prevalence of activated protein C (APC) resistance and factor V Leiden is ...
http://www.cdc.gov/genomics/hugenet/literature/2008/Hmay08.htm
www.cdc.gov
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summary
Hereditary thrombophilia in elite athletes.
[
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In 12 cases, an APC resistance caused by a factor V Leiden mutation (11 ... on the observed prevalence of APC resistance and factor II G20210A mutation in ...
http://www.ncbi.nlm.nih.gov/pubmed/11828228?ordinalpos=1&ito...
www.ncbi.nlm.nih.gov
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summary
The blood coagulation mechanism in multiple myeloma.
[
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... cytokines on endothelium, and acquired activated protein C (APC) resistance. ... of a non-factor V Leiden APC resistance has increased our understanding of the ...
http://www.ncbi.nlm.nih.gov/pubmed/12888931
www.ncbi.nlm.nih.gov
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summary
Factor V Leiden mutation and other thrombophilia markers in ...
[
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... for the presence of activated protein C (APC) resistance, antiphospholipid ... of 33 control subjects (3.03%) had APC resistance and in all of them FVL ...
http://www.ncbi.nlm.nih.gov/pubmed/15678277
www.ncbi.nlm.nih.gov
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summary
Diagnostic approach to hypercoagulable states.
[
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... protein C, and protein S deficiencies and activated protein C (APC) resistance. ... 80 % of all individuals with APC resistance carry a mutation of the ...
http://www.ncbi.nlm.nih.gov/pubmed/17125064
www.ncbi.nlm.nih.gov
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Genomics|HuGENet|Reviews|Tables2-3|Risk Factor for Placental Abruption ...
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The mission of the National Office of Public Health Genomics is to integrate advances in human genetics into ... V, resistance to APC degradation63 ...
http://www.cdc.gov/genomics/hugenet/reviews/tables/placental_Tables2-3.htm
www.cdc.gov
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summary
Two thrombotic complications in a patient with active ulcerative colitis.
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Gonera RK, Timmerhuis TP, ... revealed a transient functional APC resistance, without Factor V mutation, and ... After colectomy the APC ratio was normal. ...
http://www.ncbi.nlm.nih.gov/pubmed/9050337
www.ncbi.nlm.nih.gov
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summary
PMID 9415695
[
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334-6 Resistance to activated protein C (APC) is the most common risk factor for ... for over 90% of the APC resistance cases and is an autosomal dominant trait. ...
http://www.ncbi.nlm.nih.gov/pubmed/9415695
www.ncbi.nlm.nih.gov
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summary
Epidemiology of factor V Leiden: clinical implications.
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Inherited resistance to activated protein C (APC) has been recently recognized ... In most cases APC resistance is due to a single point mutation in the factor V ...
http://www.ncbi.nlm.nih.gov/pubmed/9763354
www.ncbi.nlm.nih.gov
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summary
Genomics|Population Research|Health Studies|Tables|Protein C and Venous ...
[
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The Role of Activated Protein C Resistance in the Pathogenesis of Venous Thrombosis ... APC-R SR. Refers to the sensitivity ratio of the plasma based ...
http://www.cdc.gov/genomics/population/file/tables/protein_c_Tables.htm
www.cdc.gov
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summary
Factor V - Wikipedia, the free encyclopedia
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... Hong Kong) make it resistant to cleavage by activated protein C ("APC resistance" ... factor V associated with resistance to activated protein C" ...
http://en.wikipedia.org/wiki/Factor_V
en.wikipedia.org
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CLEVELAND CLINIC REFERENCE LABORATORY
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APC resistance. 2 Cadasil. DNA. Test. 3 Catecholamines, Urine. 24. Hour. 3 Diagnostic. CF ... APC resistance. APC. 79045. Reference Range: 2.08 ? 2.67 (ratio) ...
http://referencelab.clevelandclinic.org/images/February2007-Dir.pdf
referencelab.clevelandclinic.org
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PMID 7590506
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344-56 Inherited resistance to activated protein C (APC) was recently recognized ... In most cases APC-resistance is due to a single point mutation in the factor V ...
http://www.ncbi.nlm.nih.gov/pubmed/7590506
www.ncbi.nlm.nih.gov
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Genomics|Population Research|Health Studies|Thrombosis in Pregnancy
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The mission of the National Office of Public Health Genomics is to integrate ... protein C, termed resistance to activated protein C (APC-R).3 APC-R/Factor V ...
http://www.cdc.gov/genomics/population/publications/thrombosis.htm
www.cdc.gov
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Factor V Leiden - Yahoo! Health
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Factor V Leiden ? Comprehensive overview covers causes and treatment of ... control factor V. This is known as an activated protein C (APC) resistance assay. ...
http://health.yahoo.com/other-other/factor-v-leiden/mayoclin...
health.yahoo.com
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11605152
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... (APC resistance) and presence of antiphospholipid antibodies, leading to deep ... IM Activated Protein C Resistance diagnosis genetics immunology Adult ...
http://www.ncbi.nlm.nih.gov/pubmed/11605152
www.ncbi.nlm.nih.gov
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Effect of tamoxifen on venous thrombosis risk factors in women without ...
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The activated protein C (APC) ratio and concentrations of antithrombin, protein ... S, but not protein C or APC resistance, might relate to the increased risk of ...
http://www.ncbi.nlm.nih.gov/pubmed/12492585
www.ncbi.nlm.nih.gov
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Venous thrombosis - Wikipedia, the free encyclopedia
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A venous thrombosis is a blood clot that forms within a vein. ... APC resistance (Factor V Leiden) Dysfibrogenemia. Hypoplasminogenemia. Familial homocysteinemia ...
http://en.wikipedia.org/wiki/Venous_thrombosis
en.wikipedia.org
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Coagulation factor V and thrombophilia: background and mechanisms.
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Since the first description of APC resistance, and in particular the description ... Protein C Resistance/blood. Activated Protein C Resistance/complications ...
http://www.ncbi.nlm.nih.gov/pubmed/17849041
www.ncbi.nlm.nih.gov
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